Granuloma Annulare Causes, Symptoms, Diagnosis, Treatment

Granuloma annulare is a chronic autoimmune dermatological disorder characterized by papules in the form of reddish bumps forming a ring shape appearance. These reddish bumps are commonly present on hands, feet, knees and elbows. This benign inflammatory condition of annular plaques on the skin is caused by an autoimmune response causing increased production of white blood cells (leukocytosis).


The exact cause of this condition is still not identified but some doctors associate this condition with thyroid disorders and diabetes mellitus. The patient seems overall healthy and no other organ or system is affected. The large amount of white blood cells circulating in the blood have some difficulty in running smoothly and thus leak through the thin capillary network to reach the undersurface of the skin, clumping there and presenting themselves as circular reddish bumps on the surface of the skin. Among granuloma annulare causes, association with some other autoimmune disorders is identified such as lupus erythematosis, addison’s disease and rheumatoid arthritis. It may also occur as a result of hypersensitivity to wheat gluten, tetanus vaccine or copper and infections along with animal, insect bites and sunlight exposure.


This condition is more common in females than males. It affects individual in all age groups however relatively rare in infants. Granuloma annulare symptoms begin in the form of small pimple like bump which advances rapidly to large and large sized lesions. Patient notices the appearance of thickened plaques, red in color, firm in consistency on the surface of forearms, hands and feet. There may be multiple rings which merge to form a large single annular plaque. It may present in four different varieties: localized, generalized, subcutaneous and perforating. It may sometimes also present on the circumference of the waist and sides and continues for years without any therapy.


Granuloma annulare diagnosis is based upon the physical examination of the bumps by a skin doctor. Biopsy can be performed in order to comfirm the diagnosis or differentiate the condition from other skin disorders and malignancies.


In most cases treatment of granuloma annulare is not needed because these lesions have the tendency of spontaneous resolution within a period of few months to few years. However the process of self-healing can be quickened by the adequate treatment options. Granuloma annulare treatment includes corticosteroids creams and ointments, adhesive patches or bandages for improved rapid results, direct injection of corticosteroids in the papules, liquid nitrogen cryotherapy to remove the lesion and replacement of it by new normal skin, laser and light therapy or excision of the lesion. All these are associated with side-effects and post-surgical pain. Oral medications are prescribed to prevent reactions of immune system. Granuloma annulare herbal product is effective in timely removal of these lesions without any side-effects and pain as seen with allopathic medications and surgical procedure. The herbal mixture improves the overall appearance of skin, leaving it smooth and soft along with completely curing this ailment in no time.


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