Sjogren’s Syndrome Causes, Symptoms, Treatment, Dignosis

Sjogren’s syndrome is the second most common systemic autoimmune disorder characterized by dry eyes and dry mouth. Autoantibodies are created against the moisture-secreting glands which affect the mucous membranes and glands of the eyes and mouth leading to inadequate tear film production and deficiency of salivary secretions respectively. A person suffering from sjogren’s syndrome might also have lupus or rheumatoid arthritis. Inflammation of the glands and other tissues of the body occur as a result of defective immune system making antibodies against these glands. It more commonly occurs in women but men can also be affected. Although it can occur at any age but most patients are above the 40 years.

Sicca Syndrome:

Sicca syndrome an autoimmune infection, otherwise called Sjogren that traditionally joins dry eyes, dry mouth, and another sickness of connective tissue, for example, rheumatoid joint pain, lupus, scleroderma or polymyositis. There is a tremendous prevalence of women. Approximately 90% of Sicca Syndrome patients is woman, generally in middle age or more experienced?

Dry Eyes Syndrome:

Dry Eyes Syndrome and dry mouth are the most widely recognized side effects.

SJOGREN’S SYNDROME CAUSES:

Sjogren’s syndrome is believed to occur as a result of familial genetic tendency. This form is called primary sjogren’s syndrome. Faulty gene transmission from parent to offspring constitute as a principal sjogren’s syndrome causes. In families having other autoimmune connective tissues diseases like lupus erythematosus, schleroderma or rheumatoid arthritis, the chance of developing sjogren’s syndrome is about 90% in women. When it is associated with these disorders then it is termed as secondary sjogren’s syndrome. A certain environmental agent such as infection from a particular virus or a bacterial strain acts as a triggering agent for the syndrome.

SJOGREN’S SYNDROME SYMPTOMS:

As a result of damage to moisture-secreting glands in eyes and mouth, two prominent symptoms of the syndrome, dry eyes and dry mouth are evident. Dry eyes manifest as keratoconjucntivitis sicca i.e implaying faulty tear film along with burning, gritting and itching of eyes. Other sjogren’s syndrome symptoms include difficulty in speaking and swallowing as a result of dry mouth. It may also affect other organs of the body such as lungs, liver, pancreas, kidney, blood vessels and brain. Dryness of nose, skin and vagina is also seen. Joint pain, swollen salivary gland, persistent dry cough and prolonged fatigues are important symptom seen in such patients.

SJOGREN’S SYNDROME COMPLICATION:

In a pregnant female with sjogren’s syndrome, the child may be born with congenital heart block or neonatal lupus erythematosus. A well-known sjogren’s syndrome’s complication is type 1 cytoglobulinemia.

SJOGREN’S SYNDROME DIAGNOSIS:

Blood tests are performed in other to measure the antibody titer for sjogren’s syndrome diagnosis. Anti-nuclear antibodies and rheumatoid factor are the two most important diagnostic antibodies found in sjogren’s syndrome. Production of tears is measured by schirmer’s test. Slit-examinations, radiological studies and biopsy is also carried out.

Dry Mouth Treatment:

On the off possibility that you think your dry mouth is bring about by certain medicine you are taking, converse with your specialist. He or she may alter the dimension you are taking or change you to an alternate medication that doesn’t bring about Dry Mouth Treatment.

SJOGREN’S SYNDROME TREATMENT:

There is no specific treatment or cure present for sjogren’s syndrome. However the condition is manageable and is controlled symptom wise.  For dry eyes, artificial tears are prescribed. Punctual plugs and goggles are also prescribed to increase humidity and retain the tears on eye surface for long time. Immunosuppressive drugs or corticosteroids are also prescribed but are associated with a large amount of side-effects. In the presence of musculoskeletal involvement, NSAIDs are used. Sjogren’s syndrome herbal product derived from pure herbal plant extracts also proved to be very effective in controlling and treating of sjogren’s syndrome. The drug has so side-effect and currently the best sjogren’s syndrome treatment option available.

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