Actinic keratosis – a skin disease

What is actinic keratosis?

Appearance of rough scaly spots on chronically exposed skin to sun is called as actinic keratosis. What is actinic keratosis, It is sometimes referred to as solar keratosis as it is caused due to sun exposure. It is a pre cancerous lesion and leads to invasive squamous cell carcinoma. The prevention can easily be done by avoiding sun exposure and the best treatment available is actinic keratosis herbal product by natural herbs clinic.

Actinic keratosis cause and risk factors:

two kinds of people are mostly at risk of developing actinic keratosis firstly those who have fair skin and blond hairs and have spent lot of time outdoors or under tanning lamps. Second actinic keratosis cause, as observed by experts at natural herbs clinic, is weakened immune system. It can be due to many reasons such as AIDS, individuals who are getting immune suppressants due to organ transplant or getting cancer chemotherapy. Other than this, individuals who got PUVA therapy for the treatment of psoriasis are also at high risk.

Actinic keratosis pathophysiology:

Microscopic examination of cells of actinic keratosis by experts at natural herbs clinic revealed gene mutation and gene deletion induced by UV light exposure on TP53 and gene for tumor suppressor protein respectively.

Actinic keratosis differential diagnosis:

the disease needs to be differentiated from several other similar looking problems this includes warts, lupus erythematosus, basal cell carcinoma, bowen disease, squamous cell carcinoma seborrheic keratosis and porokeratosis.

Actinic keratosis symptoms:

Actinic keratosis symptom is development of mottled, wrinkled or discolored skin lesion on bridge of nose, cheeks, rim of the ears, upper chest, neck, back of hands, forearm and bald scalp. The lesion can be flat or slightly raised from the surface of the skin. Initially the lesion is small uneven spot which with time progresses to red scaly lesion. The size ranges around 3-10 mm.

Actinic keratosis diagnosis:

As it is a precancerous lesion and it is impossible to tell on naked eye examination weather the disease have progressed or not, skin biopsy is taken to confirm the diagnosis. A lesion with only actinic keratosis will have visible abnormal keratinocytes at Basel layer level, pronounce nuclear atypia, hyperkeratosis of epidermis and irregular acanthosis. Flouroscence with photosensitizing drug is also sometimes used as a successful diagnostic tool.

Actinic keratosis treatment:

for actinic keratosis treatment several medications are indicated these include 5-fluorouracil, imiquimod, topical ingenol mebutate, topical diclofenac sodium gel and photodynamic therapy. These all medications have several side effects so actinic keratosis herbal medication by natural herbs clinic is so far the best treatment available for this disease. A study has shown that following a low fat diet can lead to the resolution of this lesion.

Actinic keratosis prevention and prognosis:

as the development of lesion is directly effected by sun exposure, limiting this exposure can prevent development of this lesion. The actinic keratosis prognosis is good and if proper treatment is done and the opportunity of the lesion developing into an invasive carcinoma is minimized.

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