Myasthenia gravis – a neuromuscular disorder

What is myasthenia gravis?

It is a neuromuscular disease, sometimes also known as goldflam disease. The voluntary muscles are affected and will become weak and will also easily fatigue. This happens due to defective nerve signal transmission leading to defective muscle contraction. The periorbital muscles are usually affected in the initial stage leading to ptosis and diplopia. Involuntary muscles are spared from the effects of this disease. Myasthenia gravis herbal product by natural herbs clinic is the recommended treatment.

Myasthenia gravis cause:

nerves ends at muscle fibers forming neuromuscular junction. Here signals are transmitted from nerves to the muscle fibers by the release of neurotransmitter vesicles, from the nerve endings in post synaptic cleft. This neurotransmitter then stimulates muscle fibers by binding with post synaptic acetylcholine receptors. During ocular myasthenia gravis these receptors are destroyed by auto antibodies produced by body’s own immune system. The exact trigger of immune system is not known even by the experts at natural herbs clinic but abnormally functioning thymus is the most suspected myasthenia gravis cause.

Myasthenia gravis symptom:

the main myasthenia gravis symptom as observed by experts at natural herbs clinic is muscle weakness however the severity of this weakness varies. In most cases symptoms are localized in initial stage but will progress to generalized forms in later stages. The first noticed symptom is patient’s susceptibility to fatigue where muscles become weak in a progressive manner during the period of activity while the condition tends to improve after rest. When only ocular muscles are affected which happens in only 15% of patients, it is tagged as ocular myasthenia. When facial muscles get involved, symptoms such as dysarthria, dysphagia, difficulty in chewing and development of weird facial expressions are seen. When limb muscles are affected simple activities such as walking, lifting things become a problem.

Myasthenia gravis diagnosis:

myasthenia gravis patient have some distinguishing complains on examination this include progressive muscle weakness from the start of day which improves by resting, impaired eye movements and muscle weakness which is not associated with loss of ability to feel. Myasthenia gravis diagnosis can be confirmed by several tests this includes edrophonium test, blood test, repetitive nerve stimulation test, single fiber EMG, chest X-rays, CT, pulmonary function test and muscle biopsy.

Myasthenia gravis treatment:

myasthenia gravis treatment is done to achieve two goals first increase nerve muscle signal transduction and second combat the triggered autoimmune reaction. Myasthenia gravis herbal product by natural herbs clinic is the product which have potential to treat myasthenia in both ways and improves the prognosis of the disease.

Myasthenia gravis complication:

three main complications are observed in such patients first myasthenia crisis second aspiration pneumonia due to poor functioning oropharyngeal muscles and cholinergic crisis which is a consequence of cholinesterase treatment. Respiratory failure showing the involvement of respiratory muscles is usually the end stage complication. Pneumonia in such cases leads to death and it is caused due to inability to cough by such individuals. Hypoxemia and respiratory acidosis might leave the patient somnolent.

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