Porphyria can have nervous and cutaneous manifestations

What is porphyria?

Group of disorders characterized by nervous or dermatological manifestations is known as porphyria disease. This happens due to abnormal metabolism of heme which leads to build up of heme precursors in the body. The cause is inherited gene defects. Porphyria herbal product by natural herbs clinic is recommended for its treatment.

Porphyria symptoms:

Porphyria symptoms can be divided into two types, nervous symptoms which appear in case of acute disease includes chest pain, abdominal pain, often severe, increased heart rate and blood pressure. Limb and back pain, muscle weakness, tingling, loss of sensation, cramping, vomiting and constipation, personality changes or mental disorders, agitation, confusion, and seizures. Hypothermia can also be observed during the acute episode which can last from days to weeks. Cutaneous form of the disease effect skin of the forearms, hands, face, ears and neck on which symptoms like blisters, itching, pain , swelling, increased hair growth and hyper pigmentation along with thickening of skin can occur.

What is Acute Intermittent Porphyria?

Acute Intermittent Porphyria condition is associate deficiency of the enzyme hydroxymethylbilane synthase (also called porphobilinogen deaminase).

What is porphyria cutanea tarda?

Porphyria cutanea tarda (PCT) is the most familiar kind of porphyria.

Porphyria cause:

experts at natural herbs clinic observed that all kinds of porphyrias emerge due to defect in heme metabolism. It occurs due to inherited gene defect which is autosomal dominant in nature but can also be autosomal recessive. Porphyria cutanea tarda is a kind of porphyria which is acquired. The triggers of the acute attack can be several this includes alcohol consumption, excessive iron intake, infections such as hepatitis C, fasting, smoking stress and sun exposure.

Porphyria diagnosis:

porphyria diagnosis is done on the basis of blood stool and urine analysis which will show elevated levels of porphoblinogen or its derivatives.

Porphyria differential diagnosis:

porphyria need to be differentiated from acute lymphoblastic leukemia, acute myelocytic leukemia, chronic and acute anemias, generalized anxity disorder, panic disorder, diabetic ketoacidosis, dubin-jhonson syndrome, hepatitis B and C, Hodgkin disease, hydrocarbon inhalation injury, myocardial infarction in childhood, pheochromocytoma and tyrosinemia.

Porphyria complication:

porphyria complication includes chronic renal insufficiency, repeated acute attacks increases the chances of neuropsychiatric symptoms. Experts at natural herbs clinic observed that chances of hepatocellular carcinoma also increase. In around 8% of the women pregnancy can precipitate an acute attack after which termination of pregnancy becomes necessary. Permanent skin damage can also occur in case of cutaneous disease.

Porphyria prognosis:

porphyria can be considered a lifelong disease. Some types effects the quality of life more immensely then others. Proper treatment and avoiding the triggers can increase the time span between the attacks.

Porphyria treatment:

porphyria treatment can be done by hematin, analgesics, propranolol, beta carotene supplements, and chloroquine but the best treatment presently available in the market is porphyria herbal product by natural herbs clinic.

Porphyria prevention:

the development of the symptoms can be delayed by taking some steps this include avoiding the medications which trigger the attack, avoid alcohol, eat healthy and don’t go for severe caloric restrictions, avoid smoking, minimize sun exposure as much as possible, timely treatment of infections and reduction of stress. Genetic testing can confirm if an individual have a potential of developing this condition.

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