Archives

Lichens planus- a not so well known disease

What is lichens planus?

What is lichens planus, a skin disease caused due to cell mediated immune response. It can co exist with several other immune problems including alopecia areata, vitiligo, morphes, ulcerative colitis, myasthenia gravis and dermatomyositis. Some association has been found between hepititic C virus induced liver infections and lichen planus. It is treated by lichens planus herbal product of natural herbs clinic.

Erosive lichen planus:

Erosive lichen planus is a chronic hurting situation affecting mucosal surfaces, mostly the mouth (oral lichen planus) and the genitals (vulval or penile lichen planus). A severe variant or erosive lichen planus in female is famous as the vulvovaginal gingival syndrome.

Oral lichen planus:

Oral lichen planus is appearing inside the mouth. Oral lichen planus affects 50 percent of patients with skin lichen planus but might occur without skin lesions elsewhere. The entire areas inside the mouth can be affected. There might be no symptoms but it can cause discomfort, lumps and ulcers.

Lichen planus cause:

the exact lichen planus cause is unknown but it is an immune reaction in which antigen is presented to the t-lymphocytes by langerhan cells forming epidermotrophic infiltrates leading to inflammation. Genetic correlation is also observed in some cases. Increased human leukocyte antigen B7, DR10 and DR1 were found in abundance in such cases.

Lichens planus signs and symptoms:

The lesion initially erupts from the flexure surface and then generally involve whole organ in a week, reaching to maximum size in 2- 16 weeks. Lichens planus signs and symptoms include accompanied pruritus and itching. Other then skin, mucosa can also be involved with pain and burning being the symptom if it involves oral mucosa. Other structures that can be involved are genitalias where annular glans lesions appear in men and reticulate papules or severe erosion of vulva in females occur. Nails can be affected and presents as grooving, ridging and hyperpigmentation, observed by experts at natural herbs clinic.

Lichens planus clinical variants:

the disease can have various clinical presentations this includes Hypertrophic lichen planus, Atrophic lichen planus, Erosive/ulcerative lichen planus, Follicular lichen planus (lichen planopilaris), Annular lichen planus, Linear lichen planus, Vesicular and bullous lichen planus, Actinic lichen planus, Lichen planus pigmentosus and Lichen planus pemphigoides.

Lichens planus diagnosis:

lichens planus diagnosis can be done by direct immunoflurescence which will reveal IgM deposits along with keratinocytes. The distinguishing histopathological features includes granular layer focal thickening along with hyperkeratotic epidermis, degeneration of keratinocytes in lower layers of epidermis, basement membrane having linear fibrin deposits and infiltration of T lymphocytes.

Lichens planus differential diagnosis: the disease should be differentiated from some other similar lesions including Lichen Nitidus, Lichen Simplex Chronicus, Pityriasis Rosea, Psoriasis, Guttate, Psoriasis, Plaque, Syphilis and Tinea Corporis.

Lichens planus treatment:

luckily lichen planus is a self limiting disease and resolves itself but mild to severe cases might need treatment, corticosteroids are normally recommended but as mentioned above it can lead to complications. The best product today available for lichen planus treatment is lichen planus herbal product by natural herbs clinic.

Lichens planus complication:

Lichens planus when effects oral mucosa, have the ability of malignant transformation. The experts at natural herbs clinic observed that ulcerative lesions are more prone to this transformation. The medication used to treat lichens can lead to several side effects including osteoporosis, bone marrow suppression, infection, adrenal insufficiency and growth retardation. Alopecia and hyperpigmentation of the affected area is common even after the lesion resolves.

Lichens planus prognosis:

the lichens planus prognosis can be considered good as most of the cases resolves in 18 months but reoccurrence is often observed.