Tag Archive | polycythemia vera causes

Polycythemia Vera – caused by hyperplastic bone marrow

What is Polycythemia Vera

A condition characterized by an increased number of circulating red blood cells leading to hyperviscous blood because of bone marrow hyperplasia knowns what is Polycythemia Vera. It normally also causes an increased number of other cell types that is white blood cells and platelets. Without treatment, the condition can lead to life-threatening complications. Polycythemia Vera herbal product by Natural Herbs Clinic is the treatment available for the management of this condition.

Polycythemia Vera Herbal Treatment

Polycythaemia Rubra Vera

Polycythemia Rubra Vera is the most familiar of primary polycythaemia. Polycythemia Rubra Vera is a reason by a somatic alteration in a single haematopoietic stem cell.

Polycythemia Vera Epidemiology

The disease is uncommon, effecting 0.1 – 1.6 person per million. The disease commonly affects individuals over the age of 50–70 years but can affect those in there early adult or childhood ages.

Polycythemia Vera Causes

The disease is caused because of a mutation in the gene, responsible for the production of JAK 2 protein. This mutation causes abnormal proliferation of bone marrow cells which leads to increased cell production. Researchers at Natural Herbs Clinic and other institutes found that the mutation normally occurs after birth, so the condition is acquired, rather than inherited. Males are more commonly affected than females.

Polycythemia Vera Symptoms

The Polycythemia Symptoms because of hyperviscosity of blood include breathing difficulty when lying down, dizziness, excessive bleeding, fullness in the left upper abdomen (because of the enlarged spleen), headache, itching especially after a warm bath, red colouring, especially of the face, shortness of breath and symptoms of phlebitis. Other symptoms that can also be present in some individuals are cyanosis, fatigue, red spots on skin and vision problems as observed by experts at natural herbs clinic.

Polycythemia Vera Diagnosis

The polycythemia vera diagnosis is done based on bone marrow biopsy, complete blood count with differential, comprehensive metabolic panel, erythropoietin level, genetic test for the JAK2V617F mutation, oxygen saturation of the blood, red blood cell mass, vitamin B12 level, ESR, lactate dehydrogenase test, leukocyte alkaline phosphatase, platelet aggregation test and serum uric acid test. The blood test will show elevated hematocrit, hemoglobin and erythropoietin level. Hyperplasia of the bone marrow cells will be observed on biopsy while gene mutation test will confirm the disease.

Polycythemia Vera Herbal Treatment

The Polycythemia Vera Herbal Treatment directed toward reduction of blood thickness and prevention of clotting. Phlebotomy is the procedure normally performed in a hospital environment in which 1 pint blood is removed per week until the hematocrit level comes to normal. A better remedy to combat with this problem is polycythemia Vera herbal product by Natural Herbs Clinic which is made of natural ingredients and will treat your condition at home.

Polycythemia Vera Complications

The polycythemia vera complications include formation of blood clots which can lead to pulmonary embolism and deep venous thrombosis, splenomegaly, skin problems such as itching and life-threatening blood disorders such as myelofibrosis, myelodysplastic syndrome and acute myelogenous leukemia.

Polycythemia Vera Prognosis

As the condition is chronic and takes several years to develop its accidental diagnosis is common and with the timely treatment both development of complications and progression of the symptoms can be stopped.

Polycythemia Vera Treatment, Causes, Symptoms, Diagnosis

Polycythemia Vera is a myeloproliferative blood disorder characterized by the excessive formation of red blood cells (erythrocytes) by the bone marrow. White blood cells and platelet count also increases. It is a rare bone marrow disorder. Primary disease manifestation lies in the thickening of blood caused by too many red blood cells in the circulation which might lead to clot formation. Clot formation causes the blockage of arteries and veins ultimately leading to a fatal stroke or a heart attack. Because of the increased density of blood in the vessels, the flow becomes slow and sluggish preventing adequate oxygen from reaching the tissues especially heart hence angina or heart failure results.

POLYCYTHEMIA VERA CAUSES

It affects all age groups, although incidence rises with age. It occurs more commonly in men than in women. Polycythemia Vera Causes is associated with the genetic mutation of an important gene called JAK2V617F. The exact cause of the mutation is not known. A single fault haematopoietic precursor cell in bone marrow leads to clonal expansion resulting in Polycythemia Vera. The sensitivity of erythroid precursors to erythropoietin increases, causing large production of red blood cell formation.

Polycythemia Rubra Vera

Polycythemia Rubra Vera, also called essential polycythaemia Vera, is a problem where an excess of red cells is produced in the bone marrow, with no certain cause.

Polycythemia Vera life expectancy

Polycythemia Vera life expectancy may be bargained as the infection develops to myelofibrosis, or seldom, intense leukaemia.

POLYCYTHEMIA VERA SYMPTOMS

The disease is slow and progressive, usually requiring a period of about 4 to 5 years before it presents itself. Characteristic signs and Polycythemia Vera Symptoms include the increased mass of erythrocytes (RBCs), neutrophilia (increased neutrophils than normal), thrombocytosis (increased platelet count in the blood) and splenomegaly (enlargement of the spleen). Severe burning and itching of hands and feet are found because of histamine release. Increased viscosity of blood is responsible for the following symptoms: a history of the vascular occlusive disease, dizziness, headache, gout, pruritus, mental confusion, flushed face and abdominal discomfort. Due to abnormalities of RBCs and platelet, symptoms of epistaxis, thromboembolism, gum bleeding and gastrointestinal bleeding is common.

POLYCYTHEMIA VERA COMPLICATIONS

Other than stroke and Heart Attack being a fatal polycythemia vera complication, a small group of sufferers progressively develop malignant blood disorders of acute myelogenous leukaemia or myelofibrosis.

POLYCYTHEMIA VERA DIAGNOSIS

Prognosis of the disease is strongly influenced by early diagnosis and treatment. Blood tests are performed to find out the count of cells. Complete blood picture and erythrocyte-sedimentation rate reveal and confirm the polycythemia vera diagnosis. Physical examination reveals enlarged spleen or liver and sometimes gouty nodules.

POLYCYTHEMIA VERA Herbal TREATMENT

Polycythemia Vera Herbal Treatment is based upon reducing the symptoms of the disease because no specific cure is present for it. Timely management is necessary, otherwise, it may prove fatal. Phlebotomy is performed to remove blood from the body, thus reducing the viscosity of blood associated with increased volume. Aspirin is also prescribed to prevent clot formation. Chemotherapy is indicated for its treatment but it is associated with the increased risk of developing acute myelogenous leukaemia. Radioactive isotopic injections, although suppress the bone marrow, can also lead to AML malignant transformation. Polycythemia vera herbal product cures the condition owing to its herbal constituents, which help the body restore and maintain its normal physiological functions by Natural Remedies For Polycythemia Vera and its associated symptoms in a short time.

By: Natural Herbs Clinic